PrEP is a daily pill for people who do not have HIV who want added protection. It is short for pre-exposure prophylaxis. When taken as prescribed, PrEP is highly effective in preventing HIV. Your health care provider can help you decide if PrEP is a good fit. Some things to consider: how often you (and/or your partners) use condoms; whether you know the HIV status of your partners and if they are on ongoing treatment; and/or whether you have recently had any sexually transmitted diseases (STDs).